Denise Wootten is a Professor in the Faculty of Pharmacy and Pharmaceutical Sciences at Monash University, a Senior Research Fellow of the National Health and Medical Research Council of Australia, and the Monash node leader for the ARC Centre for Cryo-EM of Membrane Proteins (CCeMMP). Prof. Wootten is an international expert in the study of G protein-coupled receptors (GPCRs), particularly the class B1 GPCR subfamily. Her research is directed towards understanding drug action at GPCRs, in particular modes of GPCR activation, signalling and regulation, biased agonism, allosteric modulation and the interaction of receptors with regulatory accessory proteins, and the application of cryo-EM to GPCR structure elucidation. Her research incorporates structural biology (cryo-EM), molecular, cellular and analytical pharmacology, computational biology, and preclinical mouse models of metabolic disease. She has published >100 peer reviewed research publications, and is an associate member of the Faculty of 1000, serves on the editorial board of the British Journal of Pharmacology and is a scientific advisor for Septerna Inc.