Peptides as antibody mimics

Peptides as antibody mimics

Peptides as antibody mimics (#110)

Gregory Winter ¹

Trinity College, Cambridge, UK

Antibodies have become established as the paramount biological drug, particularly for the treatment of cancer and autoimmune disease, and are now making inroads into other areas poorly served by chemical drugs. Even as the application of antibodies expands, Darwinian selection technologies are leading to new drug platforms, including chemically synthesised cyclic peptides with the potential to mimic antibodies. I will describe the progress in developing such mimics for clinical application.

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Authors contributing to this presentation.

Winter, G

Sir Gregory Winter shared the 2018 Nobel Prize in Chemistry for his work in phage technology and the creation of humanized monoclonal antibodies which have revolutionised medical therapeutics and brought great benefit to mankind. He undertook his seminal scientific work at the UK Medical Research Council Laboratory of Molecular Biology, Cambridge and was until recently Master of Trinity College at the University of Cambridge. He is co-founder and director of Bicycle Therapeutics, which develops fully synthetic, constrained peptide bicycles as a novel class of therapeutics.

Peptides as antibody mimics (#110)

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Winter, G

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