An Aza-Michael Route to Quaternary Ammonium Compounds and its Application to Antimicrobial Peptides — ASN Events
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  3. An Aza-Michael Route to Quaternary Ammonium Compounds and its Application to Antimicrobial Peptides

An Aza-Michael Route to Quaternary Ammonium Compounds and its Application to Antimicrobial Peptides (#287)

Rolland Lin 1 2 , Brian H. Northrop 3 , Margaret A. Brimble 1 2 4 , Alan J. Cameron 1 2 4
  1. Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Auckland, New Zealand
  2. School of Chemical Sciences, The University of Auckland, Auckland, New Zealand
  3. Chemistry, Wesleyan University, Middletown, Connecticut, USA
  4. School of Biological Sciences, The University of Auckland, Auckland, New Zealand
Publish consent withheld
  1. (1) Ongwae, G. M.; Morrison, K. R.; Allen, R. A.; Kim, S.; Im, W.; Wuest, W. M.; Pires, M. M. Broadening Activity of Polymyxin by Quaternary Ammonium Grafting. ACS Infect. Dis. 2020. https://doi.org/10.1021/acsinfecdis.0c00037.
  2. (2) Okano, A.; Isley, N. A.; Boger, D. L. Peripheral Modifications of [Ψ[CH 2 NH]Tpg 4 ]Vancomycin with Added Synergistic Mechanisms of Action Provide Durable and Potent Antibiotics. Proc Natl Acad Sci USA 2017, 201704125. https://doi.org/10.1073/pnas.1704125114.
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