Circular peptides as a new class of ligands to modulate cannabinoid type 2 receptor signaling — ASN Events
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  3. Circular peptides as a new class of ligands to modulate cannabinoid type 2 receptor signaling

Circular peptides as a new class of ligands to modulate cannabinoid type 2 receptor signaling (#372)

Natasa Tomasevic 1 , Fabiola S. Emser 1 , Edin Muratspahic 1 2 , Manuel Felkl 3 , Christian F.W. Becker 3 , Christian W. Gruber 1
  1. Institute for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria
  2. Institute for Protein Design, University of Washington, Seattle, Washington, USA
  3. Institute of Biological Chemistry, University of Vienna, Vienna, Austria
Publish consent withheld
  1. Muratspahić, E. et al. Nature-Derived Peptides: A Growing Niche for GPCR Ligand Discovery. Trends in Pharmacological Sciences 40, 309-326 (2019).
  2. Muratspahić, E. et al. Harnessing cyclotides to design and develop novel peptide GPCR ligands. RSC Chemical Biology 1, 177-191 (2020).
  3. Li, X. et al. Crystal structure of the human cannabinoid receptor CB2. Cell 176, (2019).
  4. Di Marzo, V. New approaches and challenges to targeting the endocannabinoid system. Nature Reviews Drug Discovery 17, 623–639 (2018).
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