Poster Session 2 - Wine Tasting — ASN Events

Poster Session 2 - Wine Tasting — ASN Events

Poster Session 2 - Wine Tasting

Includes Rapid Fire Poster Presentations

Structure and activity of backbone-modified class B1 GPCR agonists - Brian P Cary
Molecular tools to study the oxytocin receptor system - Monika Perisic
Covalent ligands on the rise: Development of ‘furan warhead’- equipped nanobodies - Laure Tack
Silencing oncogenic signalling with Transcription Block Survival assay-derived peptides - Andrew Brennan
In-silico Design and Discovery of Small Molecule Hits Targeting the Neurotensin Receptor 2 (NTS2) Using a Rational Peptide-to-Small Molecule Approach - Michael Desgagné

#AusPeptide2023

Development of Peptide-based Ratiometric Fluorescent Probe for Sensing Heparan sulfate and Heparin in aqueous solutions at physiological pH and Quantitative Detection of Heparan Sulfate in Live Cells. (#301)

Selective detection of methylmercury over mercury using fluorescent peptidyl probes by replacing dimethylamino group with cyclic amino rings in micelle system. (#302)

A Study on Copper(I)-catalyzed Azide-Alkyne Cycloaddtion(CuAAC) Click Reaction in different Conditions Using Ratiometric Fluorescent Probe. (#303)

Myeonggeun park

Synthesis and in vivo evaluation of a synthetic anti-cocaine nanovaccine (#304)

Harrison Y.R. Madge

Impact of peptide length on in vivo hydrogel stability and sustained drug release (#305)

α-amylase (AA) and dipeptidyl peptidase IV (DPP-IV) inhibitory bioactive peptides generated from young and mature soybean protein isolates: Characterization and identification (#306)

Maqsood Maqsood

Novel Peptides as Selective Affinity Labels of the AT2R (#307)

Proteolytic resistant antimicrobial peptide against pseudomonas aeruginosa keratitis (#308)

Venkatesh Mayandi

Antimicrobial Frog Peptide-based Combination Therapy against Mycobacterium tuberculosis (#309)

Anjana Peethambaran Menon

Targeting mucosal gastrointestinal biofilms with antimicrobial peptides (#310)

Michael Michael

Vimentin and citrullinated-vimentin in the crosstalk during THP-1 monocyte cell line differentiation and inflammasome activation. (#311)

Agata Mikolajczyk-Martinez

Ribosomal synthesis of macrocyclic D/L-α/β/γ-hybrid peptide libraries for discovery of IFNGR1 inhibitors (#312)

Combinational use of CD4 mimic with other anti-HIV agents and development of these hybrid molecules (#313)

Bioinspired peptide stapling (#314)

Richard Morewood

Computer-Aided Development of Antiviral PROTACs to Target and Degrade SARS-CoV-2 PL-Protease (#315)

Tobias D Morris

Towards structural determination of Relaxin receptor [RXFP1] (#316)

Tiffany (Theingi) Myint

Lipid Derivatisation of Polymyxin B Nonapeptide via a Chemoselective Thia-Michael Approach (#317)

Understanding IRAP inhibition using diverse substrates, inhibitors and mutagenesis (#318)

2,5-Diketopiperazine Formation Facilitated by γ-Substituted Prolines for Direct Synthesis of Tag-Attached Peptide Thioester (#319)

Late-Stage Modification of Peptides via Strain Release of [1.1.1]Propellane (#320)

Philippe Nashar

Design and rational engineering of a Batroxicidin peptide derivative for anti-cancer therapy (#321)

Malay Ranjan Nayak

Discovering Novel Natural Products to Combat Antibiotic Resistant Pathogens (#322)

Detection of peptide-Keap1 interaction and selection of Keap1-binding peptides using engineered split intein and kanamycin kinase (#323)

Progress towards the total synthesis of lexapeptide (#324)

Broadly Applicable Synthetic Method for N-Alkyl-Rich Drug-like Cyclic Peptides (#325)

Purification and Identification of the myostatin inhibitory peptides from mealworm (Tenebrio molitor larvae) protein hydrolysate in C2C12 cells (#326)

Anti-biofilm and anti-inflammatory effects of Lycosin-II isolated from spiders against multi-drug resistant bacteria. (#327)

Protecting Group-Minimized Peptide Synthesis Using Peptide Thioacid (#328)

Kounosuke Oisaki

Small Molecules with Cyclic Dipeptide and Gallic Acid Moieties Ameliorate Ferroptosis and Amyloid Toxicity Associated with Alzheimer’s Disease (#329)

Antiplasmodial peptide–drug conjugates incorporating a platelet-derived cell-penetrating peptide (#330)

Isabella Palombi

Total Synthesis, Structure-Activity Relationship Study, Bioactivity and Nephrotoxicity Evaluation of the Novel Cyclic Lipodepsipeptide Brevicidine B (#331)

Dennise Palpal-latoc

Bactericidal activities and Action mechanism of the Novel Antimicrobial Peptide Hylin a1 and its analog peptides against Acinetobacter baumannii infection (#332)

Design and synthesis of asymmetric covalently tethered cyclic peptide nanotubes (#333)

William Parsons

Acid-stable ester linkers for the synthesis of immobilized peptides (#334)

Auditing structural bias in machine learning-guided antimicrobial peptide discovery (#335)

Machine learning-guided discovery of antifungal peptides from hymenopteran venoms (#336)

Mitigating the structural bias in discovering membrane-active antimicrobial peptides using inverse protein folding (#337)

Exploring the structure-activity landscape of non-canonical peptides with MAP4 fingerprinting (#338)

Structural effects in aza-peptide bond formation reaction (#339)

Selectivity of aqueous N-thiophosphorylation of peptides (#340)

Robyn E Poulton

Photocontrollable probes for the investigation of neuropeptide signalling and emotional memory (#342)

Konstantin Raabe

Developing novel inhibitors for survivin anti-apoptotic function (#343)

Saharnaz Rafiee

An amide to thioamide substitution improves the permeability and bioavailability of macrocyclic peptides (#344)

Design and Preparation of Atactic Artificial L/D-Proteolytic Enzymes (#345)

Mads Liep Ramsing

Targeting the incorporation of hydroxy-acids in NRPS biosynthesis (#346)

Minuri Ratnayake

Reducing the Bottlenecks in the Drug Discovery Peptide Workflow (#347)

Influence of D-arg and D-lys on the structure and antibacterial activities of computer-made peptides (#348)

Samilla B Rezende

Mending achy breaky hearts: cyclic peptide TropL01 as therapeutic for heart failure (#349)

Daniela Rojas-Azofeifa

Selectively cleavable protecting groups for the epsilon-amino group of lysine (#350)

Exploration of the peroxidase-like activity of Cytochrome P450 CYP121 from Mycobacterium tuberculosis (#351)

Photoaffinity labelling for the elucidation of mycocyclosin target protein(s) (#352)

How cell penetrating peptides escape endosomes? (#353)

Ultrashort histidine-based lipopeptides show more potent activities than ampicillin against Escherichia coli and Staphylococcus aureus (#354)

Remmer L. Salas

Design, characterization and evaluation of a protide with therapeutic potential for control of fish farming diseases. (#355)

Proteomic Profiling and Antimicrobial Potential of Epidermal Mucus from Chilean Aquaculture Fish Species (#356)

Protease-activated receptor 2 is activated by peptides that modulate doxorubicin-induced apoptosis in cancer cells (#357)

Himani Deepak Shah

Hymenopteran venom bradykinin-like peptides mimic vertebrate bradykinin peptide hormones to cause pain and deter predators. (#358)

Design and evaluation of a novel cell penetrating peptide for enhanced corneal wound healing (#359)

Peptide-based PROTAC specific degradation of endogenous Tau proteins (#360)

Stimuli-Responsive Coiled Coil-Based Nanostructures (#361)

Esteban Suarez Picado

Virus-directed enzyme prodrug therapy (#362)

Superfast Desulfurization for Protein Chemical Synthesis and Modification (#363)

A new hope for the peptide antibiotic ramoplanin (#364)

Julien Tailhades

Detection of Cytoplasmic Peptide:N-Glycanase Activity inside Cells Using Split Inteins and NanoLuc Luciferase (#366)

Tsuyoshi Takahashi

Chemically Modified Amino Acids as Site-Specific ¹⁹F-NMR Probes in Proteins (#367)

Oral Hepcidin Peptidomimetics – Potent Pharmacodynamic Activities in Rodents and Non-Human Primates (#368)

Intracellular application of an asparaginyl endopeptidase for producing recombinant head-to-tail cyclic proteins (#369)

T. M. Simon Tang

Designing cyclic peptide FXIIa inhibitors by optimising loop 6 in a cyclotide scaffold (#370)

Synthesis and Biological Evaluations of Teixobactin Analogues against Gram-positive Bacteria and Biofilms (#371)

Tsz Ying Teresa To

Circular peptides as a new class of ligands to modulate cannabinoid type 2 receptor signaling (#372)

Natasa Tomasevic

Spider beta-hairpin peptide engineered to target protein:protein interactions, reach the cytosol, and kill cancer cells (#373)

Sonia Troeira Henriques

Investigating the inhibitory property of double mutated hCT on hCT fibrillization via the relevant peptide fragments (#374)

Multiply-Entangled De Novo Proteins (#375)

Dattatraya Uttam Ukale

Biocompatible peptide bicyclisation using dicyanopyridine amino acids (#376)

Novel peptide therapeutics for Alzheimer’s disease (#377)

Detection of peptide-MDM2 interactions and selection of MDM2-binding peptides using engineered split intein and kanamycin kinase (#378)

Yutaro Watanabe

Towards Genetic Encoding of 4-Azatryptophan and 6-Azatryptophan (#379)

Adarshi P. Welegedara

Harnessing Thioesterase Domains for Probing Antibiotic Modifications (#380)

Total Synthesis of Complex Peptide Natural Products (#381)

The saltwater crocodile defensin CpoBD13 is a novel pH‑sensing antifungal peptide (#382)

Synthetic C5a peptide or anaphylatoxin C5a protein induce Rab5a-C5aR1 trafficking, chemotaxis and chemokine secretion in human macrophages (#383)

Computational design of α-conotoxins to target specific nicotinic acetylcholine receptor subtypes. (#384)

Palladium-Catalysed Lage-Stage C–H Arylation of Peptides (#385)

Fungal oxepine natural product: biosynthesis and engineering (#386)

RGDX₁X₂ motif regulates integrin αvβ5-mediated cell adhesion (#387)

Staple-biased phage display for targeting ALT-positive cancers (#388)

Jackie Tsz Ki Yau

Lycosin-II Exhibits Antifungal Activity and Inhibits Dual-Species Bioﬁlm by Candida albicans and Staphylococcus aureus (#389)

Design of peptide-based probes for detecting phospholipid head group (#390)

Incorporating alkylthioaryl linkage in macrocyclic peptidomimetic design: Discovery of novel melanocortin ligands for melanoma imaging and therapy (#391)

Targeting inflammation using genetic reprogramming in mRNA display (#392)

Enhancing peptide-based vaccine immunogenicity: role of cyclic decapeptide as a multivalent scaffold (#393)

Jiahui JZ Zhang

Developing a PCSK9 degrader for lowering cholesterol (#394)

Development of bifunctional antibody with immune checkpoint inhibitory effect using Lasso-grafting (#395)

Structural studies of the mechanism of voltage-sensing in voltage-gated ion channels using cyclised nanodiscs (#396)

Elucidating Binding Pathway of Peptide Ligands to the Neurotensin 1 Receptor: from Solution Phase to Final Binding Conformation (#247)

Herodion Hartono